Filling gaps in a metabolic network using expression information

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چکیده

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Filling gaps in a metabolic network using expression information

MOTIVATION The metabolic models of both newly sequenced and well-studied organisms contain reactions for which the enzymes have not been identified yet. We present a computational approach for identifying genes encoding such missing metabolic enzymes in a partially reconstructed metabolic network. RESULTS The metabolic expression placement (MEP) method relies on the coexpression properties of...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2004

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/bth930